We are a young and dynamic group based in the Matière et Système Complexes laboratory in the heart of the Paris Rive Gauche district within the Université Paris Cité.
We study the mechanical properties of model tissues in the context of muscle differentiation and tumour progression. Our aim is to determine and understand the organisation and mechanics of these tissues, but also to be able to modify their fate by physical constraints.
RESEARCH INTERESTS
Architecture of model tissues under physical constraints, Mechanobiology of model tissues, Multicellular communication and dynamics, Muscle cell differentiation, Tumoral progression.
TOOLS
Magnetic nanoparticles, multicellular aggregates, manipulation of magnetic aggregates, tissue rheology, tissue microscopy, 2-photons microscopy.
Team members
Lorijn VAN DER SPEK
PhD Student
Alain RICHERT
Assistant
Florence DELORT
Research Engineer
Latest News
Shaping 3D minimal model tissues with mechanical constraints to orchestrate muscle differentiation
Have a look on our new article https://www.nature.com/articles/s42003-025-09252-9#peer-review
Read more
Gefluc – Les entreprises contre le cancer
Myriam Reffay has just received funding from Gefluc Paris – IDF (Groupement des Entreprises Françaises dans la Lutte contre le Cancer) for her project entitled: ‘Probing mechanical properties during tumor[…]
Read more